Biopython is an open-source collection of non-commercial Python modules for computational biology and bioinformatics. It makes robust and well-tested code easily accessible to researchers. Python is an object-oriented programming language and is a suitable choice for automation of common tasks. The availability of reusable libraries saves development time and lets researchers focus on addressing scientific questions. Biopython is constantly updated and maintained by a large team of volunteers across the globe. Biopython contains parsers for diverse bioinformatic sequence, alignment, and structure formats. Sequence formats include FASTA, FASTQ, GenBank, and EMBL. Alignment formats include Clustal, BLAST, PHYLIP, and NEXUS. Structural formats include the PDB, which contains the 3D atomic coordinates of the macromolecules. It has provisions to access information from biological databases like NCBI, Expasy, PBD, and BioSQL. This can be used in scripts or incorporated into their software. Biopython contains a standard sequence class, sequence alignment, and motif analysis tools. It also has clustering algorithms, a module for structural biology, and a module for phylogenetics analysis. == History == The development of Biopython began in 1999, and it was first released in July 2000. First "semi-complete" and "semi-stable" release was done in March 2001 and December 2002 respectively. It was developed during a similar time frame and with analogous goals to other projects that added bioinformatics capabilities to their respective programming languages, including BioPerl, BioRuby and BioJava. Early developers on the project included Jeff Chang, Andrew Dalke and Brad Chapman, though over 100 people have made contributions to date. In 2007, a similar Python project, namely PyCogent, was established. The initial scope of Biopython involved accessing, indexing and processing biological sequence files. The retrieved data from common biological databases will then be parsed into a python data structure. While this is still a major focus, over the following years added modules have extended its functionality to cover additional areas of biology. The key challenge in the design of parsers for bioinformatics file formats is the frequency at which the data formats change. This is due to inadequate curation of the structure of the data, and changes in the database contents. This problem is overcome by the application of a standard event-oriented parser design (see Key features and examples). As of version 1.77, Biopython no longer supports Python 2. The current stable release of Biopython version 1.85 was released on 15 January 2025. It only supports Python 3 and the recent releases of Biopython require NumPy (and not Numeric). == Design == Wherever possible, Biopython follows the conventions used by the Python programming language to make it easier for users familiar with Python. For example, Seq and SeqRecord objects can be manipulated via slicing, in a manner similar to Python's strings and lists. It is also designed to be functionally similar to other Bio projects, such as BioPerl. It is organized into modular sub-packages, e.g., Bio.Seq, Bio.Align, Bio.PDB, Bio.Entrez each of them useful in a different bioinformatics domain. It used principles, like encapsulation and polymorphism, notably in classes Seq, SeqRecord, and Bio.PDB.Structure. It can also interoperate with other Python tools (Pandas, Matplotlib and SciPy). Biopython can read and write most common file formats for each of its functional areas, and its license is permissive and compatible with most other software licenses, which allows Biopython to be used in a variety of software projects. == Requirements == Biopython is currently supported and tested with the following Python implementations: Python 3 or PyPy3 NumPy == Key features and examples == === Input and output === Biopython can read and write to a number of common formats. When reading files, descriptive information in the file is used to populate the members of Biopython classes, such as SeqRecord. This allows records of one file format to be converted into others. Very large sequence files can exceed a computer's memory resources, so Biopython provides various options for accessing records in large files. They can be loaded entirely into memory in Python data structures, such as lists or dictionaries, providing fast access at the cost of memory usage. Alternatively, the files can be read from disk as needed, with slower performance but lower memory requirements. === Sequences === A core concept in Biopython is the biological sequence, and this is represented by the Seq class. A Biopython Seq object is similar to a Python string in many respects: it supports the Python slice notation, can be concatenated with other sequences and is immutable. This object includes both general string-like and biological sequence-specific methods. It is best to store information about the biological type (DNA, RNA, protein) separately from the sequence, rather than using an explicit alphabet argument. === Sequence annotation === The SeqRecord class describes sequences, along with information such as name, description and features in the form of SeqFeature objects. Each SeqFeature object specifies the type of the feature and its location. Feature types can be ‘gene’, ‘CDS’ (coding sequence), ‘repeat_region’, ‘mobile_element’ or others, and the position of features in the sequence can be exact or approximate. === Accessing online databases === Through the Bio.Entrez module, users of Biopython can download biological data from NCBI databases. Each of the functions provided by the Entrez search engine is available through functions in this module, including searching for and downloading records. === Phylogeny === The Bio.Phylo module provides tools for working with and visualising phylogenetic trees. A variety of file formats are supported for reading and writing, including Newick, NEXUS and phyloXML. Common tree manipulations and traversals are supported via the Tree and Clade objects. Examples include converting and collating tree files, extracting subsets from a tree, changing a tree's root, and analysing branch features such as length or score. Rooted trees can be drawn in ASCII or using matplotlib (see Figure 1), and the Graphviz library can be used to create unrooted layouts (see Figure 2). === Genome diagrams === The GenomeDiagram module provides methods of visualising sequences within Biopython. Sequences can be drawn in a linear or circular form (see Figure 3), and many output formats are supported, including PDF and PNG. Diagrams are created by making tracks and then adding sequence features to those tracks. By looping over a sequence's features and using their attributes to decide if and how they are added to the diagram's tracks, one can exercise much control over the appearance of the final diagram. Cross-links can be drawn between different tracks, allowing one to compare multiple sequences in a single diagram. === Macromolecular structure === The Bio.PDB module can load molecular structures from PDB and mmCIF files, and was added to Biopython in 2003. The Structure object is central to this module, and it organises macromolecular structure in a hierarchical fashion: Structure objects contain Model objects which contain Chain objects which contain Residue objects which contain Atom objects. Disordered residues and atoms get their own classes, DisorderedResidue and DisorderedAtom, that describe their uncertain positions. Using Bio.PDB, one can navigate through individual components of a macromolecular structure file, such as examining each atom in a protein. Common analyses can be carried out, such as measuring distances or angles, comparing residues and calculating residue depth. === Population genetics === The Bio.PopGen module adds support to Biopython for Genepop, a software package for statistical analysis of population genetics. This allows for analyses of Hardy–Weinberg equilibrium, linkage disequilibrium and other features of a population's allele frequencies. This module can also carry out population genetic simulations using coalescent theory with the fastsimcoal2 program. === Wrappers for command line tools === Biopython previously included command-line wrappers for tools such as BLAST, Clustal, EMBOSS, and SAMtools. This option allowed users to run external tool commands from within the code using specialized Biopython classes. However, Bio.Application modules and their wrappers have deprecated and will be removed in future Biopython releases. The main reason for this is the high maintenance burden of updating them with the evolving external tools. The recommended approach is to directly construct and execute command-line tool commands using Python’s built-in subprocess module. This method provides flexibility and removes the dependency on the Biopython wrappers. subprocess is a native Python module useful for running ext
Perusall
Perusall is a social web annotation tool intended for use by students at schools and universities. It allows users to annotate the margins of a text in a virtual group setting that is similar to social media—with upvoting, emojis, chat functionality, and notification. It also includes automatic AI grading. == History == Perusall began as a research project at Harvard University. It later became an educational product for students and teachers. As of 2024, Perusall states more than 5 million students have used the tool at over 5,000 educational institutions in 112 countries." == Functionality == Perusall integrates with learning management systems such as Moodle, Canvas and Blackboard to aid with collaborative annotation. The tool supports annotation of a range of media including text, images, equations, videos, PDFs and snapshots of webpages.
Steerable filter
In image processing, a steerable filter is an orientation-selective filter that can be computationally rotated to any direction. Rather than designing a new filter for each orientation, a steerable filter is synthesized from a linear combination of a small, fixed set of "basis filters". This approach is efficient and is widely used for tasks that involve directionality, such as edge detection, texture analysis, and shape-from-shading. The principle of steerability has been generalized in deep learning to create equivariant neural networks, which can recognize features in data regardless of their orientation or position. == Example == A common example of a steerable filter is the first derivative of a two-dimensional Gaussian function. This filter responds strongly to oriented image features like edges. It is constructed from two basis filters: the partial derivative of the Gaussian with respect to the horizontal direction ( x {\displaystyle x} ) and the vertical direction ( y {\displaystyle y} ). If G ( x , y ) {\displaystyle G(x,y)} is the Gaussian function, and G x {\displaystyle G_{x}} and G y {\displaystyle G_{y}} are its partial derivatives (which measure the rate of change in the x {\displaystyle x} and y {\displaystyle y} directions, respectively), a new filter G θ {\displaystyle G_{\theta }} oriented at an angle θ {\displaystyle \theta } can be synthesized with the formula: G θ = cos ( θ ) G x + sin ( θ ) G y {\displaystyle G_{\theta }=\cos(\theta )G_{x}+\sin(\theta )G_{y}} Here, the basis filters G x {\displaystyle G_{x}} and G y {\displaystyle G_{y}} are weighted by cos ( θ ) {\displaystyle \cos(\theta )} and sin ( θ ) {\displaystyle \sin(\theta )} to "steer" the filter's sensitivity to the desired orientation. This is equivalent to taking the dot product of the direction vector ( cos θ , sin θ ) {\displaystyle (\cos \theta ,\sin \theta )} with the filter's gradient, ( G x , G y ) {\displaystyle (G_{x},G_{y})} . == Generalization in deep learning: Equivariant neural networks == The concept of steerability is foundational to equivariant neural networks, a class of models in deep learning designed to understand symmetries in data. A network is considered equivariant to a transformation (like a rotation) if transforming the input and then passing it through the network produces the same result as passing the input through the network first and then transforming the output. Formally, for a transformation T {\displaystyle T} and a network f {\displaystyle f} , this property is defined as f ( T ( input ) ) = T ( f ( input ) ) {\displaystyle f(T({\text{input}}))=T(f({\text{input}}))} . This built-in understanding of geometry makes models more data-efficient. For example, a network equivariant to rotation does not need to be shown an object in multiple orientations to learn to recognize it; it inherently understands that a rotated object is still the same object. This leads to better generalization and performance, particularly in scientific applications. === Mathematical foundation === Equivariant neural networks use principles from group theory to create operations that respect geometric symmetries, such as the SO(3) group for 3D rotations or the E(3) group for rotations and translations. Instead of learning standard filter kernels, these networks learn how to combine a fixed set of basis kernels. These basis functions are chosen so that they have well-defined behaviors under transformation groups. Spherical harmonics are frequently used as basis functions because they form a complete set of functions that behave predictably under rotation, making them ideal for creating steerable 3D kernels. Features within the network are treated as geometric tensors, which are mathematical objects (like scalars or vectors) that are "typed" by their behavior under transformations. These types correspond to the irreducible representations (irreps) of the group. The tensor product is the fundamental operation used to combine these typed features in a way that preserves equivariance, guaranteeing that the network as a whole respects the desired symmetry. Frameworks like e3nn simplify the construction of these networks by automating the complex mathematics of irreducible representations and tensor products. === Applications === Steerable and equivariant models are highly effective for problems with inherent geometric symmetries. Examples include: Protein structure analysis: SE(3)-equivariant networks can process 3D molecular structures while respecting their rotational and translational symmetries. 3D Point cloud processing: Rotation-equivariant filters built from steerable spherical functions can perform tasks like 3D shape classification. Computational chemistry: E(3)-equivariant graph neural networks are used to model interatomic potentials for molecular dynamics simulations, creating highly accurate and data-efficient models of physical systems.
Phase stretch transform
Phase stretch transform (PST) is a computational approach to signal and image processing. One of its utilities is for feature detection and classification. PST is related to time stretch dispersive Fourier transform. It transforms the image by emulating propagation through a diffractive medium with engineered 3D dispersive property (refractive index). The operation relies on symmetry of the dispersion profile and can be understood in terms of dispersive eigenfunctions or stretch modes. PST performs similar functionality as phase-contrast microscopy, but on digital images. PST can be applied to digital images and temporal (time series) data. It is a physics-based feature engineering algorithm. == Operation principle == Here the principle is described in the context of feature enhancement in digital images. The image is first filtered with a spatial kernel followed by application of a nonlinear frequency-dependent phase. The output of the transform is the phase in the spatial domain. The main step is the 2-D phase function which is typically applied in the frequency domain. The amount of phase applied to the image is frequency dependent, with higher amount of phase applied to higher frequency features of the image. Since sharp transitions, such as edges and corners, contain higher frequencies, PST emphasizes the edge information. Features can be further enhanced by applying thresholding and morphological operations. PST is a pure phase operation whereas conventional edge detection algorithms operate on amplitude. == Physical and mathematical foundations of phase stretch transform == Photonic time stretch technique can be understood by considering the propagation of an optical pulse through a dispersive fiber. By disregarding the loss and non-linearity in fiber, the non-linear Schrödinger equation governing the optical pulse propagation in fiber upon integration reduces to: E o ( z , t ) = 1 2 π ∫ − ∞ ∞ E ~ i ( 0 , ω ) ⋅ e − i β 2 z ω 2 2 ⋅ e i ω t d ω {\displaystyle E_{o}(z,t)={\frac {1}{2\pi }}\int _{-\infty }^{\infty }{\tilde {E}}_{i}(0,\omega )\cdot e^{\frac {-i\beta _{2}z\omega ^{2}}{2}}\cdot e^{i\omega {t}}\,d\omega } (1) where β 2 {\displaystyle \beta _{2}} = GVD parameter, z is propagation distance, E o ( z , t ) {\displaystyle E_{o}(z,t)} is the reshaped output pulse at distance z and time t. The response of this dispersive element in the time-stretch system can be approximated as a phase propagator as presented in H ( ω ) = e i φ ( ω ) = e i ∑ m = 0 ∞ φ m ( ω ) = ∏ m = 0 ∞ H m ( ω ) {\displaystyle H(\omega )=e^{i\varphi (\omega )}=e^{i\sum _{m=0}^{\infty }\varphi _{m}(\omega )}=\prod _{m=0}^{\infty }H_{m}(\omega )} (2) Therefore, Eq. 1 can be written as following for a pulse that propagates through the time-stretch system and is reshaped into a temporal signal with a complex envelope given by E o ( t ) = 1 2 π ∫ − ∞ ∞ E ~ i ( ω ) ⋅ H ( ω ) ⋅ e i ω t d ω {\displaystyle E_{o}(t)={\frac {1}{2\pi }}\int _{-\infty }^{\infty }{\tilde {E}}_{i}(\omega )\cdot H(\omega )\cdot e^{i\omega t}\,d\omega } (3) The time stretch operation is formulated as generalized phase and amplitude operations, S { E i ( t ) } = ∫ − ∞ + ∞ F { E i ( t ) } ⋅ e i φ ( ω ) ⋅ L ~ ( ω ) ⋅ e i ω t d ω {\displaystyle \mathbb {S} \{E_{i}(t)\}=\int _{-\infty }^{+\infty }{\mathcal {F}}\{E_{i}(t)\}\cdot e^{i\varphi (\omega )}\cdot {\tilde {L}}(\omega )\cdot e^{i\omega {t}}d\omega } (4) where e i φ ( ω ) {\displaystyle e^{i\varphi (\omega )}} is the phase filter and L ~ ( ω ) {\displaystyle {\tilde {L}}(\omega )} is the amplitude filter. Next the operator is converted to discrete domain, S { E i [ n ] } = 1 N ∑ u = 0 N − 1 F F T { E i ( n ) } ⋅ K ~ ( u ) ⋅ L ~ ( u ) ⋅ e i 2 π N u n {\displaystyle \mathbb {S} \{E_{i}[n]\}={\frac {1}{N}}\sum _{u=0}^{N-1}FFT\{E_{i}(n)\}\cdot {\tilde {K}}(u)\cdot {\tilde {L}}(u)\cdot e^{i{\frac {2\pi }{N}}un}} (5) where u {\displaystyle u} is the discrete frequency, K ~ ( u ) {\displaystyle {\tilde {K}}(u)} is the phase filter, L ~ ( u ) {\displaystyle {\tilde {L}}(u)} is the amplitude filter and FFT is fast Fourier transform. The stretch operator S { } {\displaystyle \mathbb {S} \{\}} for a digital image is then S { E i [ n , m ] } = 1 M N ∑ v = 0 N − 1 ∑ u = 0 M − 1 F F T 2 { E i ( n , m ) } ⋅ K ~ ( u , v ) ⋅ L ~ ( u , v ) ⋅ e i 2 π M u m ⋅ e i 2 π N v n {\displaystyle \mathbb {S} \{E_{i}[n,m]\}={\frac {1}{MN}}\sum _{v=0}^{N-1}\sum _{u=0}^{M-1}FFT^{2}\{E_{i}(n,m)\}\cdot {\tilde {K}}(u,v)\cdot {\tilde {L}}(u,v)\cdot e^{i{\frac {2\pi }{M}}um}\cdot e^{i{\frac {2\pi }{N}}vn}} (6) In the above equations, E i [ n , m ] {\displaystyle E_{i}[n,m]} is the input image, n {\displaystyle n} and m {\displaystyle m} are the spatial variables, F F T 2 {\displaystyle FFT^{2}} is the two-dimensional fast Fourier transform, and u {\displaystyle u} and v {\displaystyle v} are spatial frequency variables. The function K ~ ( u , v ) {\displaystyle {\tilde {K}}(u,v)} is the warped phase kernel and the function L ~ ( u , v ) {\displaystyle {\tilde {L}}(u,v)} is a localization kernel implemented in frequency domain. PST operator is defined as the phase of the Warped Stretch Transform output as follows P S T { E i [ n , m ] } ≜ ∡ { S { E i [ x , y ] } } {\displaystyle PST\{E_{i}[n,m]\}\triangleq \measuredangle \{\mathbb {S} \{E_{i}[x,y]\}\}} (7) where ∡ { } {\displaystyle \measuredangle \{\}} is the angle operator. == PST kernel implementation == The warped phase kernel K ~ ( u , v ) {\displaystyle {\tilde {K}}(u,v)} can be described by a nonlinear frequency dependent phase K ~ ( u , v ) = e i φ ( u , v ) {\displaystyle {\tilde {K}}(u,v)=e^{i\varphi (u,v)}} While arbitrary phase kernels can be considered for PST operation, here we study the phase kernels for which the kernel phase derivative is a linear or sublinear function with respect to frequency variables. A simple example for such phase derivative profiles is the inverse tangent function. Consider the phase profile in the polar coordinate system φ ( u , v ) = φ polar ( r , θ ) = φ polar ( r ) {\displaystyle \varphi (u,v)=\varphi _{\text{polar}}(r,\theta )=\varphi _{\text{polar}}(r)} From d φ ( r ) d r = tan − 1 ( r ) {\displaystyle {\frac {d\varphi (r)}{dr}}=\tan ^{-1}(r)} we have φ ( r ) = r tan − 1 ( r ) − 1 2 log ( r 2 + 1 ) {\displaystyle \varphi (r)=r\tan ^{-1}(r)-{\frac {1}{2}}\log(r^{2}+1)} Therefore, the PST kernel is implemented as φ ( r ) = S ⋅ ( W r ) ⋅ tan − 1 ( W r ) − 1 2 log ( 1 + ( W r ) 2 ) ( W r max ) ⋅ tan − 1 ( W r max ) − 1 2 log ( 1 + ( W r max ) 2 ) {\displaystyle \varphi (r)=S\cdot {\frac {(Wr)\cdot \tan ^{-1}(Wr)-{\frac {1}{2}}\log(1+(Wr)^{2})}{(Wr_{\max })\cdot \tan ^{-1}(Wr_{\max })-{\frac {1}{2}}\log(1+(Wr_{\max })^{2})}}} where S {\displaystyle S} and W {\displaystyle W} are real-valued numbers related to the strength and warp of the phase profile == Applications == PST has been used for edge detection in biological and biomedical images as well as synthetic-aperture radar (SAR) image processing, as well as detail and feature enhancement for digital images. PST has also been applied to improve the point spread function for single molecule imaging in order to achieve super-resolution. The transform exhibits intrinsic superior properties compared to conventional edge detectors for feature detection in low contrast visually impaired images. The PST function can also be performed on 1-D temporal waveforms in the analog domain to reveal transitions and anomalies in real time. == Open source code release == On February 9, 2016, a UCLA Engineering research group has made public the computer code for PST algorithm that helps computers process images at high speeds and "see" them in ways that human eyes cannot. The researchers say the code could eventually be used in face, fingerprint, and iris recognition systems for high-tech security, as well as in self-driving cars' navigation systems or for inspecting industrial products. The Matlab implementation for PST can also be downloaded from Matlab Files Exchange. However, it is provided for research purposes only, and a license must be obtained for any commercial applications. The software is protected under a US patent. The code was then significantly refactored and improved to support GPU acceleration. In May 2022, it became one algorithm in PhyCV: the first physics-inspired computer vision library.
Automated attendant
In telephony, an automated attendant (also auto attendant, auto-attendant, autoattendant, automatic phone menus, AA, or virtual receptionist) allows callers to be automatically transferred to an extension without the intervention of an operator/receptionist. Many AAs will also offer a simple menu system ("for sales, press 1, for service, press 2," etc.). An auto attendant may also allow a caller to reach a live operator by dialing a number, usually "0". Typically the auto attendant is included in a business's phone system such as a PBX, but some services allow businesses to use an AA without such a system. Modern AA services (which now overlap with more complicated interactive voice response or IVR systems) can route calls to mobile phones, VoIP virtual phones, other AAs/IVRs, or other locations using traditional land-line phones or voice message machines. == Feature description == Telephone callers will recognize an automated attendant system as one that greets calls incoming to an organization with a recorded greeting of the form, "Thank you for calling .... If you know your party's extension, you may dial it any time during this message." Callers who have a touch-tone (DTMF) phone can dial an extension number or, in most cases, wait for operator ("attendant") assistance. Since the telephone network does not transmit the DC signals from rotary dial telephones (except for audible clicks), callers who have rotary dial phones have to wait for assistance. On a purely technical level it could be argued that an automated attendant is a very simple kind of IVR however, in the telecom industry the terms IVR and auto attendant are generally considered distinct. An automated attendant serves a very specific purpose (replace live operator and route calls), whereas an IVR can perform all sorts of functions (telephone banking, account inquiries, etc.). An AA will often include a directory which will allow a caller to dial by name in order to find a user on a system. There is no standard format to these directories, and they can use combinations of first name, last name, or both. The following lists common routing steps that are components of an automated attendant: Transfer to extension Transfer to voicemail Play message (i.e., "our address is ...") Go to a sub-menu Repeat choices In addition, an automated attendant would be expected to have values for the following: '0' – where to go when the caller dials '0' Timeout – what to do if the caller does nothing (usually go to the same place as '0') Default mailbox – where to send calls if '0' is not answered (or is not pointing to a live person) == Background == PBXs (private branch exchanges) or PABXs (private automatic branch exchanges) are telephone systems that serve an organization that has many telephone extensions but fewer telephone lines (sometimes called "trunks") that connect that organization to the rest of the global telecommunications network. While persons within an enterprise served by a PBX can call each other by dialing their extension numbers, incoming calls, i.e., calls originating from a telephone not served by the PBX but intended for a party served by the PBX, required assistance from a switchboard operator (also called a "switchboard attendant") or a telephone service called DID ("direct inward dialing"). Direct inward dialing has advantages such as rapid connection to the destination party and disadvantages including cost, lack of identification of the called organization and use of ten-digit telephone numbers. Automated attendants provide, among many other things, a way for an external caller to be directed to an extension or department served by a PBX system without using direct inward dialing or without switchboard attendant assistance. == History == Automated attendants are not part of voicemail systems. Voice messaging (or voicemail or VM) technology has existed since the late 1970s; in the early 1980s companies provided voice-prompting systems that allowed callers to reach (route the call) to an intended party, not necessarily to leave a message. Automated attendant systems are also referred to as automated menu systems and much early work in this field was done by Michael J. Freeman, Ph.D. == Time-based routing == Many auto attendants will have options to allow for time-of-day routing, as well as weekend and holiday routing. The specifics of these features will depend entirely on the particular automated attendant, but typically there would be a normal greeting and routing steps that would take place during normal business hours, and a different greeting and routing for non-business hours.
Play Integrity API
Play Integrity API (formerly known as SafetyNet) consists of several application programming interfaces (APIs) offered by the Google Play Services to support security sensitive applications and enforce DRM. Currently, these APIs include device integrity verification, app verification, recaptcha and web address verification. It uses an environment called DroidGuard to perform the attestation. == Attestation == The SafetyNet Attestation API, one of the APIs under the SafetyNet umbrella, provides verification that the integrity of the device is not compromised. In practice, non-official ROMs such as LineageOS fail the hardware attestation and thus prevent the user from using a non-compliant ROM with third-party apps (mainly banking) that require the API. Due to this, some consider this a monopolistic practice deterring the entrance of competing mobile operating systems in the market. It requires a network connection to Google servers and validates the hardware signatures. Amongst the checks, the API looks for bootloader unlock status, ROM signatures, kernel strings, it also uses AVB2.0 and dm-verity attestations. Upon successful checks, Google Play will mark the device as Certified. The attestation runs in an environment called DroidGuard (com.google.android.gms.unstable). The SafetyNet Attestation API (one of the four APIs under the SafetyNet umbrella) has been deprecated. As of 6 October 2023, Google planned to replace it with the Play Integrity API by the end of January 2025. The transition ended on 20 May 2025, breaking applications which hadn't been updated. These attestations are offered by Google Play Services and thus are not available on free Android environments, like AOSP. Therefore, developers can require the API to be available and may refuse to execute on AOSP builds. == Google Play Protect == Under the same umbrella, Play Protect is a mechanism to find and remove "vulnerable" apps from one's Android device as well as store apps. Although it's meant to scan for malware-containing apps, it also looks for non-DRM compliant apps. == Criticism == Multiple groups have criticised SafetyNet and the Play Integrity API. Criticisms include that it offers weaker protection compared to alternatives such as Android's hardware attestation API, which provides a stronger form of verification while having the ability to remain compatible with more secure Android operating systems like GrapheneOS. Critics argued it undermines competition by effectively requiring developers to rely on Google's proprietary services, strengthening its monopoly over the Android ecosystem and disadvantaging alternative, privacy-focused operating systems. Users have also developed tools, such as the Play Integrity Fix module for Magisk/KernelSU/APatch, which tricks the attestation using leaked fingerprints of vulnerable devices. Furthermore, some have questioned the effectiveness of the attestation, claiming it does not deliver the level of security promised by Google and instead serves more as a form of vendor lock-in than a meaningful security measure. Activists have also raised concerns that it may violate antitrust and competition laws, like the Digital Markets Act.
AdBlock
AdBlock is an ad-blocking browser extension for Google Chrome, Apple Safari (desktop and mobile), Firefox, Samsung Internet, Microsoft Edge and Opera. AdBlock allows users to prevent page elements, such as advertisements, from being displayed. It is free to download and use, and it includes optional donations to the developers. The AdBlock extension was created on December 8, 2009, which is the day that supports for extensions was added to Google Chrome. It was one of the first Google Chrome extensions that was made. Since 2016, AdBlock has been based on the Adblock Plus source code. In July 2018, AdBlock acquired uBlock, a commercial ad-blocker owned by uBlock LLC and based on uBlock Origin. In April 2021, eyeo GmbH (developer of Adblock Plus) announced its purchase of AdBlock, Inc (formerly BetaFish, Inc). == Crowdfunding == Gundlach launched a crowdfunding campaign on Crowdtilt in August 2013 in order to fund an ad campaign to raise awareness of ad-blocking and to rent a billboard at Times Square. After the one-month campaign, it raised $55,000. == Sales and acceptable ads == AdBlock was sold to an anonymous buyer in 2015 and on October 15, 2015, Gundlach's name was taken down from the site. In the terms of the deal, the original developer Michael Gundlach left operations to Adblock's continuing director, Gabriel Cubbage, and as of October 2, 2015, AdBlock began participating in the Acceptable Ads program. Acceptable Ads identifies "non-annoying" ads, which AdBlock shows by default. The intent is to allow non-invasive advertising, to either maintain support for websites that rely on advertising as a main source of revenue or for websites that have an agreement with the program. == Filters == AdBlock uses EasyList, the same filter syntax as Adblock Plus for Firefox, and natively supports the use of a number of filter lists. == Partnership with Amnesty International == On March 12, 2016, in support of World Day Against Cyber Censorship, and in partnership with Amnesty International, instead of blocking ads, AdBlock replaced ads with banners linked to articles on Amnesty's website, written by prominent free speech advocates such as Edward Snowden, to raise awareness of government-imposed online censorship and digital privacy issues around the world. The campaign was met with both praise and criticism, with AdBlock's CEO, Gabriel Cubbage, defending the decision in an essay on AdBlock's website, saying "We’re showing you Amnesty banners, just for today, because we believe users should be part of the conversation about online privacy. Tomorrow, those spaces will be vacant again. But take a moment to consider that in an increasingly information-driven world, when your right to digital privacy is threatened, so is your right to free expression." Meanwhile, Simon Sharwood of The Register characterized Cubbage's position as "'You should control your computer except when we feel political', says AdBlock CEO". == AdBlock for Firefox == On September 13, 2014, the AdBlock team released a version for Firefox users, ported from the code for Google Chrome, released under the same free software license as the original Adblock. The extension was removed on April 2, 2015, by an administrator on Mozilla Add-ons. On December 7, 2015, the official AdBlock site's knowledge base article stated that with version 44 or higher of Firefox desktop and Firefox Mobile, AdBlock will not be supported. The last version of Adblock for those platforms will work on older versions of Firefox. AdBlock was released again on Mozilla Add-ons on November 17, 2016. On April 1, 2012, Adblock developer Michael Gundlach tweaked the code to display LOLcats instead of simply blocking ads. Initially developed as a short-lived April Fools joke, the response was so positive that CatBlock was continued to be offered as an optional add-on supported by a monthly subscription. On October 23, 2014, the developer decided to end official support for CatBlock, and made it open-source, under GPLv3 licensing, as the original extension.